I have tried many kinds of nutritional supplements and herbs to overcome persistent brain excitement from stress. It caused irritability and dysfunctional sleep. Fixing mineral imbalance with mineral supplements is something that has worked for many. However, there are only a few ones that work among various kinds of supplements. This difference comes from bioavailability, the proportion of a drug or other substance that enters the circulation when introduced into the body. But high bioavailability doesn’t guarantee a better effect because it may not be absorbed well by the target organ, e.g., brain. Talk to your doctor about which supplement is best for you.