Ozone therapy in combination with injection therapy results in about 75% of chronic pain sufferers to become permanently pain free. Chronic pain occurs in areas of the body that contain ligaments, cartilage or articular surfaces which typically have only 1/10th the circulation that is seen in other connective tissues. This makes them especially vulnerable to the effects of decreased oxygen utilization and aging, which further compromises circulation. When these areas become traumatized a significant amount of edema and inflammation only serve to further decrease circulation. Prolozone therapy with natural anti-inflammatory medications, vitamins & minerals gives the tissues what they need to heal.