Prolozone or Ozone Therapy has remarkable functions for immune management because of the increased oxygen utilization at a cellular level. Patients report increased energy, increased stamina, increased resistance to cold and flu’s, the disappearance of unresolved symptoms and an overall increased sense of well-being. The success of the ozone treatment is dependent on the practitioner’s skill, judgment & the proper integration of other skills including, nutrition, natural medicines, acupuncture, detoxification. Many patients follow these recommendations to resolve a specific acute or chronic ailment and then continue periodically with ozone treatments as an immune system seasonal tune-up.