Ensure that unwanted prescriptions don’t pose a risk to you and others. Instead of flushing them down the toilet or throwing them into the garbage, which can harm the environment, follow these tips for disposing of unused or expired medications safely: Check your medicine cabinet at least twice a year for expired prescription and non-prescription medications (including vitamins and other natural supplements), as well as any medications you no longer need. Look at the medication for signs of discolouration or strange odours. Place expired medications in a paper bag and take them to your local pharmacy for proper disposal.